Christian Coleman has been charged under anti-doping procedures for failing to properly file his whereabouts information on three occasions.
If found guilty, Coleman could face a potential two-year ban which would rule him out of the 2019 World Championships in Doha and the Tokyo 2020 Olympic Games.
The US Anti-Doping Agency (USADA) confirmed to Olympic Channel that Coleman had been notified of the charge. The sprinter will have a hearing on September 4 in which he can make his case. USADA has stated it will make a decision by September 5.
Coleman said in a statement, "I'm not a guy who takes any supplements at all, so I'm never concerned about taking drugs tests, at any time. What has been widely reported concerning filing violations is simply not true.
"I am confident the upcoming hearing on 4 September will clear the matter and I will compete at the World Championships in Doha this fall." - Christian Coleman
USADA said: "Given Mr. Coleman has now publicly commented on his case, we can confirm that he has been notified and charged under the USADA Protocol of a potential anti-doping rule violation for failing to properly file his whereabouts information."
"Under the World Anti-Doping Code three whereabouts failures within a 12-month period may be considered an anti-doping rule violation."
The fastest man on the planet right now, Coleman ran this year's leading 100m in 9.81 seconds at the California Diamond League in June.
The 2017 World Championships silver medallist is the favourite for many to take gold in Doha and at the Tokyo 2020 Olympic Games.
But that may be jeopardised by these charges.
USADA gave more specifics into the case to Olympic Channel saying:
"Two of the three test attempts on Mr. Coleman were USADA directed and one of the attempts was initiated by the Athletics Integrity Unit (AIU). Given this, the case is proceeding under the USADA Protocol but we are working closely with the AIU on this matter."
"We have expedited the case under the USADA rules," the statement continues, "and Mr. Coleman has agreed to have the three-person independent American Arbitration Association/North American Court of Arbitration for Sport (AAA/CAS) arbitration panel hear the case on September 4 and issue its decision by the end of the following day, well before the IAAF World Championships."