The double Olympic champion took a year out from action after taking bronze at the PyeongChang 2018 Olympics.
In that time she married former American bobsledder Travis Armbruster, and asked to be released by Bobsleigh Canada citing irreconcilable differences with head coach Todd Hays.
But having initially denied her wish to go and compete for the United States, Bobsleigh Canada granted her request at the end of September.
And in her first international outing for 21 months, the 34-year-old teamed up with PyeongChang silver medallist Lauren Gibbs to take World Cup victory at Lake Placid.
What it takes to win
Speaking ahead of her return, Humphries said she spent her time off with her family and her husband, calling it "a busy yet very productive and calming year off".
And she's looking forward to learning from her new Team USA colleagues, having competed against them throughout her career up until now.
Speaking in Lake Placid, Humphries said, "They bring the experience from being a part of this team with this coaching. At the same point, I've been doing this sport now 15 years so I know what it takes to win, to be the best.
"I'll bring the experience from that side of it, but I'm definitely looking to learn from them as well so together as a team we can be very cohesive and hopefully be very successful this year."
Humphries the bobsled superstar
Humphries took gold on home ice at Vancouver 2010 alongside Heather Moyse.
While Moyse then concentrated on her rugby career, Humphries enjoyed continued success with Chelsea Valois in behind.
But Moyse was back for Sochi 2014 and the pair retained their title ahead of Elana Meyers Taylor and Lauryn Williams into silver.
Humphries struggled initially with new brakewoman Melissa Lotholz as Meyers took the world titles in 2015 and 2017 with Germany's Turin 2006 gold medallist Anja Schneiderheinze-Stoeckel claiming the crown in 2016.
Lotholz was replaced by track athlete Phylicia George and she and Humphries took bronze in PyeongChang with another German pair, Mariama Jamanka and Lisa Buckwitz, winning gold from Meyers Taylor and Gibbs.
With Meyers Taylor due to give birth to her first child in March and taking the season off, Humphries is currently the US number one although her old rival insists she will be back for Beijing 2022.