In the men's draw, Federer could play Djokovic in the quarter-finals.

Serena Williams and sister Venus could face each other in the third round of the U.S. Open, as the tournament's draw was unveiled in New York City.

That would be the earliest Grand Slam meeting for the pair since the 1998 Australian Open, when they played in the second round.

Serena returns to Flushing Meadows after missing last year's event due to giving birth to her daughter Alexis Olympia.

The 36-year-old is 17th seed after organisers improved her ranking from 26th, given her long absence from the courts.

Find out here why her comeback story could become a memorable one!

Sisters could face off

Six-time U.S. Open champion Serena leads 17-12 in the head-to-head with her sister, but first has to get past Magda Linette from Poland in round one.

Venus opens against 2004 winner Svetlana Kuznetsova, who claimed the WTA title in Washington early this month.

Serena Venus Hug
Serena Venus Hug

If they do meet in the third round, one of the Williams' sisters could then possibly play the world number one Simona Halep.

Serena and Venus last faced each other in New York in the 2015 quarter-finals, with Serena prevailing in three sets.

Venus won the most recent meeting in the third round of Indian Wells in March, her sister's first tournament after maternity leave.

In the rest of the women's draw, defending champion Sloane Stephens opens against Evgeniya Rodin and is set for a potential third-round match against two-time runner-up Victoria Azarenka.

No. 2 seed Caroline Wozniacki will start against 2011 winner Sam Stosur.

Nadal US Open
Nadal US Open

Spanish derby

In the men's draw, defending champion Rafa Nadal will face compatriot David Ferrer in the first round.

The two Spaniards have met 30 times on the Tour, including the 2013 French Open final won by Nadal.

Ferrer was once ranked number 3, but has dropped to no. 148 and, at 36 years old, may be playing in the U.S. for the final time.

Nadal could then face last year's runner-up Kevin Anderson in the last eight.

His half of the draw also includes former US Open winners Juan Martin del Potro and Andy Murray.

During the event, the Argentine had also the chance to speak live with an astronaut...

World number 2 Roger Federer opens against Yoshihito Nishioka from Japan and could play Novak Djokovic in the quarter-finals.

2016 champion Stan Wawrinka was given a wild card after skipping the 2017 tournament due to injury, and faces No. 8 seed Gregory Dimitrov in the headline match of the men's singles first round.

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